Second time I watched it, first time was during its theatrical release.
Still a very powerful movie. The slow rhythm and the cinematography create a very heavy atmosphere, fit for the universe and message the movie conveys.
Some of the shots give a Dune vibe, nice to see this so many years before the first Dune movie.
Definitely recommended if you like SF and dystopian universes
Of course, take your time! I think Blade Runner 2049 is such a deep and complex film that you have to let all the ideas percolate anyway.